Soviet influx opens new era

MicroED opens a new era for biological structure determination.

In 2013 we unveiled the cryo-electron microscopy (CryoEM) method of MicroED, or three-dimensional (3D) electron diffraction of microscopic crystals. Here tiny 3D crystals of biological material are used in an electron microscope for diffraction data collection under cryogenic conditions. The data is indexed, integrated, merged and scaled using standard X-ray crystallography software to determin...

Mitochondrial medicine: a new era in medicine opens new windows and brings new challenges.

Reading Plato one might not be surprised by the apparent paradox in the ability of mitochondria to promote both life and death: On the one hand, they are the major producers of energy in the cell, and on the other hand, they can steal the life of their host “at will.” Mitochondria can sense the supply of fuel (they are important O2 sensors) and via the production of mediators (reactive O2 speci...

The largest cohort study opens a new era for the management of heart failure in Japan.

eart failure is the common feature of the endstage for any type of cardiovascular disease (CVD) and is one of the most important causes of high morbidity and mortality in developed countries. This is also the situation in Japan, mainly because of rapid aging of the population, and increased survivors of serious CVD because of the recent advances in therapeutic strategies. Although it has been t...

Unraveling the Threads of History: Soviet-Era Monuments and Post-Soviet National Identity in Moscow

Pentacam opens eyes to new diagnostic possibilities